Computational Functional Genomics

The main focus of our group is to develop predictive models of transcriptional regulation by integrating large-scale datasets to shed light on regulatory processes that are condition-specific. In conjunction with high-throughput experimental techniques, we will leverage such models to identify functional variants and mechanisms of action driving disease. Specifically, we are interested in investigating early stages of neural development using a combination of genomic profiling, functional genomics and computational analysis.